Can't be done, you'll need to convert to lat/long. Also, if its not right next to a tarmac'd road, the thing won't be able to work out how to get there and when you do "navigate to", it will sit there "calculating" for ever, until you press cancel. So make sure the OS grid ref is the start of a green lane next to a road, if that's what you are heading to.
Also, if you do "add favourite" and its eg on a car park off the road a little bit, it will accept the waypoint but never be able to navigate you there for the above reason! So you need to be aware of this and mark waypoints at the edge/entrance to places you might want to go to again, etc.